pentobarbital will lessen the level or effect of methylprednisolone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.Keep an eye on Intently (one)pentobarbital will lower the extent or effect of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Chec